celiac disease, an intestinal inflammatory disease with auto immune system features. the ingestion of gluten triggers immune system responses in the human body ,generally causing severe gastrointestinal pain, as well as other long time problem including malnutrition and fatigue. although this symptom and further intestinal can be difficult and present a financial burden. and because of this, many scientists for treatment for celiac disease.
the immune system of people with celiac disease is triggered when incompletely-digested gluten peptides go between the cells of the lamina propria in the small intestine or pass through the space between the epithelial cells. this immune responses result in the disassembly of the tight junction in the intestine and create an opening. A NEW DRUG CALLED LARZOTIDE ACETATE supposedly work to prevent this opening. A study to test the efficacy of this medicine was done on adults with biopsy-proven celiac disease. the participants who received the active larazotide acetate and ingested gluten reported less severe symptoms than those receiving the placebo study medication while on the gluten challenge.
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